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Publications

Home / Publications

Sparse Independent Component Analysis with an Application to Cortical Surface fMRI Data in Autism

Wang, Z., Gaynanova, I., Aravkin, A., & Risk, B. B. (2024). Sparse Independent Component Analysis with an Application to Cortical Surface fMRI Data in Autism. Journal of the American Statistical Association, 1–22.

Featured Publications

Lower Prevalence of Asymptomatic Alzheimer’s Disease Among Healthy African Americans

Lah JJ, Tian G, Risk BB, Hanfelt JJ, Wang L, Zhao L, Hales CM, Johnson ECB, Elmor MB, Malakauskas SJ, Heilman C, Wingo TS, Dorbin CD, Davis CP, Thomas TI, Hajjar IM, Levey AI, Parker MW. Lower Prevalence of Asymptomatic Alzheimer’s Disease Among Healthy African Americans. Ann Neurol. 2024 Jun 25. doi: 10.1002/ana.26960. PMID: 38924596.

singR: An R Package for Simultaneous Non-Gaussian Component Analysis for Data Integration.

Wang, L., I. Gaynanova, and B.B. Risk. singR: An R Package for Simultaneous Non-Gaussian Component Analysis for Data Integration. The R Journal. 2024;15(4).

Mixture of Regressions with Multivariate Responses for Discovering Subtypes in Alzheimer’s Biomarkers with Detection Limits.

Tian G, Hanfelt J, Lah J, Risk BB. Mixture of regressions with multivariate responses for discovering subtypes in Alzheimer’s biomarkers with detection limits. Data Sci Sci. 2024;3(1). doi: 10.1080/26941899.2024.2309403. Epub 2024 Mar 6. PubMed PMID: 38680829; PubMed Central PMCID: PMC11044119.

Feasibility of Multiparametric Perfusion Assessment in Diabetic Foot Ulcer Using Intravoxel Incoherent Motion and Blood Oxygenation-Level Dependent MRI.

Edwards SJ, Yao J, Schechter MC, Fayfman M, Santamarina G, Feiweier T, Blanco G, Alvarez J, Risk BB, Rajani R, Reiter DA. Feasibility of Multiparametric Perfusion Assessment in Diabetic Foot Ulcer Using Intravoxel Incoherent Motion and Blood Oxygenation-Level Dependent MRI. J Magn Reson Imaging. 2024 May;59(5):1555-1566. doi: 10.1002/jmri.28955. Epub 2023 Aug 19. PubMed PMID: 37596872; PubMed Central PMCID: PMC10875144.

Comparisons of healthy human brain temperature predicted from biophysical modeling and measured with whole brain MR thermometry.

Sung D, Risk BB, Kottke PA, Allen JW, Nahab F, Fedorov AG, Fleischer CC. Comparisons of healthy human brain temperature predicted from biophysical modeling and measured with whole brain MR thermometry. Sci Rep. 2022 Nov 11;12(1):19285. doi: 10.1038/s41598-022-22599-x. PubMed PMID: 36369468; PubMed Central PMCID: PMC9652378.

Effects of orientation-dependent susceptibility on MR chemical shift brain thermometry.

Wang KJ, Sung D, Risk BB, Allen JW, Fleischer CC. Effects of orientation-dependent susceptibility on MR chemical shift brain thermometry. Magn Reson Imaging. 2023 Jan;95:59-62. doi: 10.1016/j.mri.2022.10.007. Epub 2022 Oct 20. PubMed PMID: 36273626; PubMed Central PMCID: PMC9744186.

Interpretive JIVE: Connections with CCA and an application to brain connectivity.

Murden RJ, Zhang Z, Guo Y, Risk BB. Interpretive JIVE: Connections with CCA and an application to brain connectivity. Front Neurosci. 2022;16:969510. doi: 10.3389/fnins.2022.969510. eCollection 2022. PubMed PMID: 36312020; PubMed Central PMCID: PMC9614436.

Stability of patch-turnover relationships under equilibrium and nonequilibrium metapopulation dynamics driven by biogeography.

Beissinger SR, Peterson SM, Hall LA, Van Schmidt N, Tecklin J, Risk BB, Richmond OM, Kovach TJ, Kilpatrick AM. Stability of patch-turnover relationships under equilibrium and nonequilibrium metapopulation dynamics driven by biogeography. Ecol Lett. 2022 Nov;25(11):2372-2383. doi: 10.1111/ele.14111. Epub 2022 Oct 9. PubMed PMID: 36209497; PubMed Central PMCID: PMC9828715.

Accounting for motion in resting-state fMRI: What part of the spectrum are we characterizing in autism spectrum disorder?.

Nebel MB, Lidstone DE, Wang L, Benkeser D, Mostofsky SH, Risk BB. Accounting for motion in resting-state fMRI: What part of the spectrum are we characterizing in autism spectrum disorder?. Neuroimage. 2022 Aug 15;257:119296. doi: 10.1016/j.neuroimage.2022.119296. Epub 2022 May 10. PubMed PMID: 35561944; PubMed Central PMCID: PMC9233079.

Featured Publications

Multimodal magnetic resonance imaging reveals distinct sensitivity of hippocampal subfields in asymptomatic stage of Alzheimer’s disease

Wu J, Shahid SS, Lin Q, Hone-Blanchet A, Smith JL, Risk BB, Bisht AS, Loring DW, Goldstein FC, Levey AI, Lah JJ, Qiu D. Multimodal magnetic resonance imaging reveals distinct sensitivity of hippocampal subfields in asymptomatic stage of Alzheimer’s disease. Front Aging Neurosci. 2022;14:901140. doi: 10.3389/fnagi.2022.901140. eCollection 2022. PubMed PMID: 36034141; PubMed Central PMCID: PMC9413400.

Technology-enhanced visual desensitization home exercise program for post-concussive visually induced dizziness: a case series.

Hurtado JE, Heusel-Gillig L, Risk BB, Trofimova A, Abidi SA, Allen JW, Gore RK. Technology-enhanced visual desensitization home exercise program for post-concussive visually induced dizziness: a case series. Physiother Theory Pract. 2022 Aug;38(8):985-994. doi: 10.1080/09593985.2020.1815259. Epub 2020 Sep 21. PubMed PMID: 32955968.

Resting-State Brain Temperature: Dynamic Fluctuations in Brain Temperature and the Brain-Body Temperature Gradient.

Sung D, Risk BB, Wang KJ, Allen JW, Fleischer CC. Resting-State Brain Temperature: Dynamic Fluctuations in Brain Temperature and the Brain-Body Temperature Gradient. J Magn Reson Imaging. 2023 Apr;57(4):1222-1228. doi: 10.1002/jmri.28376. Epub 2022 Jul 29. PubMed PMID: 35904094; PubMed Central PMCID: PMC9884314

Carotid webs produce greater hemodynamic disturbances than atherosclerotic disease: a DSA time-density curve study.

Park CC, El Sayed R, Risk BB, Haussen DC, Nogueira RG, Oshinski JN, Allen JW. Carotid webs produce greater hemodynamic disturbances than atherosclerotic disease: a DSA time-density curve study. J Neurointerv Surg. 2022 Jul;14(7):729-733. doi: 10.1136/neurintsurg-2021-017588. Epub 2021 Jul 27. PubMed PMID: 34315802; PubMed Central PMCID: PMC9209666.

Group linear non-Gaussian component analysis with applications to neuroimaging.

Zhao Y, Matteson DS, Mostofsky SH, Nebel MB, Risk BB. Group linear non-Gaussian component analysis with applications to neuroimaging. Comput Stat Data Anal. 2022 Jul;171. doi: 10.1016/j.csda.2022.107454. Epub 2022 Feb 22. PubMed PMID: 35992040; PubMed Central PMCID: PMC9390952.

Utilization and Comparative Effectiveness of Uterine Artery Embolization versus Hysterectomy for Severe Postpartum Hemorrhage: A National Inpatient Sample Study.

Webster LA, Newsome J, Guo M, Lee S, Majdalany BS, Gichoya J, Platner M, Garcia-Reyes K, Duszak R Jr, Liu Y, Risk B, Cwiak CA, Kokabi N. Utilization and Comparative Effectiveness of Uterine Artery Embolization versus Hysterectomy for Severe Postpartum Hemorrhage: A National Inpatient Sample Study. J Vasc Interv Radiol. 2022 Apr;33(4):427-435.e4. doi: 10.1016/j.jvir.2021.12.004. Epub 2021 Dec 13. PubMed PMID: 34915166.

On the reproducibility of quantitative susceptibility mapping and its potential as a clinical biomarker: A comment on Cogswell et al. 2021.

Risk BB, Qiu D. On the reproducibility of quantitative susceptibility mapping and its potential as a clinical biomarker: A comment on Cogswell et al. 2021. Neuroimage. 2021 Dec 15;245:118646. doi: 10.1016/j.neuroimage.2021.118646. Epub 2021 Oct 11. PubMed PMID: 34648959.

Management of Splenic Trauma in Contemporary Clinical Practice: A National Trauma Data Bank Study.

Chahine AH, Gilyard S, Hanna TN, Fan S, Risk B, Johnson JO, Duszak R Jr, Newsome J, Xing M, Kokabi N. Management of Splenic Trauma in Contemporary Clinical Practice: A National Trauma Data Bank Study. Acad Radiol. 2021 Nov;28 Suppl 1:S138-S147. doi: 10.1016/j.acra.2020.11.010. Epub 2020 Dec 4. PubMed PMID: 33288400.

Statistical learning of blunt cerebrovascular injury risk factors using the elastic net.

Cooper ME, Risk B, Corey A, Fountain AJ, Allen JW. Statistical learning of blunt cerebrovascular injury risk factors using the elastic net. Emerg Radiol. 2021 Oct;28(5):929-937. doi: 10.1007/s10140-021-01949-8. Epub 2021 May 27. PubMed PMID: 34046756.

Simultaneous Non-Gaussian Component Analysis

Benjamin B. Risk. Irina Gaynanova. “Simultaneous non-Gaussian component analysis (SING) for data integration in neuroimaging.” Ann. Appl. Stat. 15 (3) 1431 – 1454, September 2021.

Graphic Narrative Versus Journal Article for Teaching Medical Students About P Values: A Randomized Trial.

Tigges S, Krupinski E, Luhanga U, Schulman D, Risk B. Graphic Narrative Versus Journal Article for Teaching Medical Students About P Values: A Randomized Trial. J Am Coll Radiol. 2021 Aug;18(8):1176-1178. doi: 10.1016/j.jacr.2021.03.013. Epub 2021 May 9. PubMed PMID: 33980421.

Surface-Based Connectivity Integration: An atlas-free approach to jointly study functional and structural connectivity.

Cole M, Murray K, St-Onge E, Risk B, Zhong J, Schifitto G, Descoteaux M, Zhang Z. Surface-Based Connectivity Integration: An atlas-free approach to jointly study functional and structural connectivity. Hum Brain Mapp. 2021 Aug 1;42(11):3481-3499. doi: 10.1002/hbm.25447. Epub 2021 May 6. PubMed PMID: 33956380; PubMed Central PMCID: PMC8249904.

Which multiband factor should you choose for your resting-state fMRI study?

Risk BB, Murden RJ, Wu J, Nebel MB, Venkataraman A, Zhang Z, Qiu D. Which multiband factor should you choose for your resting-state fMRI study? Neuroimage. 2021 Jul 1;234:117965. doi: 10.1016/j.neuroimage.2021.117965. Epub 2021 Mar 17. PubMed PMID: 33744454; PubMed Central PMCID: PMC8159874.

Featured Publications

Scalable Bayesian matrix normal graphical models for brain functional networks.

Kundu S, Risk BB. Scalable Bayesian matrix normal graphical models for brain functional networks. Biometrics. 2021 Jun;77(2):439-450. doi: 10.1111/biom.13319. Epub 2020 Jul 10. PubMed PMID: 32569385.

Interrater Reliability of NI-RADS on Posttreatment PET/Contrast-enhanced CT Scans in Head and Neck Squamous Cell Carcinoma.

Hsu D, Rath TJ, Branstetter BF, Anzai Y, Phillips CD, Juliano AF, Mosier KM, Bazylewicz MP, Poliashenko SM, Kulzer MH, Rhyner PA, Risk B, Wiggins RH, Aiken AH. Interrater Reliability of NI-RADS on Posttreatment PET/Contrast-enhanced CT Scans in Head and Neck Squamous Cell Carcinoma. Radiol Imaging Cancer. 2021 May;3(3):e200131. doi: 10.1148/rycan.2021200131. PubMed PMID: 34018845; PubMed Central PMCID: PMC8183259.

Contemporary Management of Pediatric Blunt Splenic Trauma: A National Trauma Databank Analysis.

Shinn K, Gilyard S, Chahine A, Fan S, Risk B, Hanna T, Johnson JO, Hawkins CM, Xing M, Duszak R Jr, Newsome J, Kokabi N. Contemporary Management of Pediatric Blunt Splenic Trauma: A National Trauma Databank Analysis. J Vasc Interv Radiol. 2021 May;32(5):692-702. doi: 10.1016/j.jvir.2020.11.024. Epub 2021 Feb 23. PubMed PMID: 33632588.

Personalized predictions and non-invasive imaging of human brain temperature

Sung D, Kottke PA, Risk BB, Allen JW, Nahab F, Fedorov AG, Fleischer CC. Personalized predictions and non-invasive imaging of human brain temperature. Communications physics. 2021 April; 4(1):68.

Impact of sampling depth on pathogen detection in pit latrines.

Capone D, Chigwechokha P, de Los Reyes FL 3rd, Holm RH, Risk BB, Tilley E, Brown J. Impact of sampling depth on pathogen detection in pit latrines. PLoS Negl Trop Dis. 2021 Mar;15(3):e0009176. doi: 10.1371/journal.pntd.0009176. eCollection 2021 Mar. PubMed PMID: 33651818; PubMed Central PMCID: PMC7954291.

ACE of space: estimating genetic components of high-dimensional imaging data.

Risk BB, Zhu H. ACE of space: estimating genetic components of high-dimensional imaging data. Biostatistics. 2021 Jan 28;22(1):131-147. doi: 10.1093/biostatistics/kxz022. PubMed PMID: 31215618; PubMed Central PMCID: PMC7846136.

Structured Curriculum Vitae Scoring as a Standardized Tool for Selecting Interview Candidates for Academic Neuroradiology Faculty Positions.

Braileanu M, Risk BB, Kadom N, Mullins ME, Krupinski EA, Saindane AM, Weinberg BD. Structured Curriculum Vitae Scoring as a Standardized Tool for Selecting Interview Candidates for Academic Neuroradiology Faculty Positions. Curr Probl Diagn Radiol. 2020 Nov-Dec;49(6):377-381. doi: 10.1067/j.cpradiol.2019.07.002. Epub 2019 Jul 9. PubMed PMID: 31326142.

Characterization of dysregulated glutamine metabolism in human glioma tissue with (1)H NMR.

Ekici S, Risk BB, Neill SG, Shu HK, Fleischer CC. Characterization of dysregulated glutamine metabolism in human glioma tissue with (1)H NMR. Sci Rep. 2020 Nov 24;10(1):20435. doi: 10.1038/s41598-020-76982-7. PubMed PMID: 33235296; PubMed Central PMCID: PMC7686482.

Percutaneous Bone Biopsy for Diabetic Foot Osteomyelitis: A Systematic Review and Meta-Analysis.

Schechter MC, Ali MK, Risk BB, Singer AD, Santamarina G, Rogers HK, Rajani RR, Umpierrez G, Fayfman M, Kempker RR. Percutaneous Bone Biopsy for Diabetic Foot Osteomyelitis: A Systematic Review and Meta-Analysis. Open Forum Infect Dis. 2020 Oct;7(10):ofaa393. doi: 10.1093/ofid/ofaa393. eCollection 2020 Oct. PubMed PMID: 33134407; PubMed Central PMCID: PMC7590897.

Optimized truncation to integrate multi-channel MRS data using rank-R singular value decomposition.

Sung D, Risk BB, Owusu-Ansah M, Zhong X, Mao H, Fleischer CC. Optimized truncation to integrate multi-channel MRS data using rank-R singular value decomposition. NMR Biomed. 2020 Jul;33(7):e4297. doi: 10.1002/nbm.4297. Epub 2020 Apr 6. PubMed PMID: 32249522; PubMed Central PMCID: PMC7317403.

Linear non-Gaussian component analysis via maximum likelihood

Risk BB, Matteson DS, Ruppert D. Linear non-Gaussian component analysis via maximum likelihood. Journal of the American Statistical Association. 2019; 114(525):332. doi: 10.1080/01621459.2017.1407772.

Optimization and testing in linear non‐Gaussian component analysis

Jin Z, Risk BB, Matteson DS. Optimization and testing in linear non‐Gaussian component analysis. Statistical analysis and data mining. 2019 March; 12:141-156. doi: 10.1002/sam.11403.

Diagnostic radiology resident perspectives on fellowship training and career interest in emergency radiology.

Herr KD, Risk B, Hanna TN. Diagnostic radiology resident perspectives on fellowship training and career interest in emergency radiology. Emerg Radiol. 2018 Dec;25(6):653-658. doi: 10.1007/s10140-018-1633-8. Epub 2018 Aug 31. PubMed PMID: 30167828.

Impacts of simultaneous multislice acquisition on sensitivity and specificity in fMRI.

Risk BB, Kociuba MC, Rowe DB. Impacts of simultaneous multislice acquisition on sensitivity and specificity in fMRI. Neuroimage. 2018 May 15;172:538-553. doi: 10.1016/j.neuroimage.2018.01.078. Epub 2018 Feb 3. PubMed PMID: 29408461.

Note on bias from averaging repeated measurements in heritability studies.

Risk BB, Zhu H. Note on bias from averaging repeated measurements in heritability studies. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E122. doi: 10.1073/pnas.1719250115. Epub 2017 Dec 29. PubMed PMID: 29288225; PubMed Central PMCID: PMC5777080.

A metapopulation approach to predict species range shifts under different climate change and landscape connectivity scenarios

Mestre F, Risk BB, Mira A, Beja P, Pita R. A metapopulation approach to predict species range shifts under different climate change and landscape connectivity scenarios. Ecological Modelling. 2017 September; 359:406-414. doi: 10.1016/j.ecolmodel.2017.06.013.

JIVE integration of imaging and behavioral data.

Yu Q, Risk BB, Zhang K, Marron JS. JIVE integration of imaging and behavioral data. Neuroimage. 2017 May 15;152:38-49. doi: 10.1016/j.neuroimage.2017.02.072. Epub 2017 Feb 27. PubMed PMID: 28246033.

Ecological and Social Factors Constrain Spatial and Temporal Opportunities for Mating in a Migratory Songbird.

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Kaiser SA, Risk BB, Sillett TS, Webster MS. Ecological and Social Factors Constrain Spatial and Temporal Opportunities for Mating in a Migratory Songbird. Am Nat. 2017 Mar;189(3):283-296. doi: 10.1086/690203. Epub 2017 Feb 1. PubMed PMID: 28221825.

Spatiotemporal mixed modeling of multi-subject task fMRI via method of moments.

Risk BB, Matteson DS, Spreng RN, Ruppert D. Spatiotemporal mixed modeling of multi-subject task fMRI via method of moments. Neuroimage. 2016 Nov 15;142:280-292. doi: 10.1016/j.neuroimage.2016.05.038. Epub 2016 May 19. PubMed PMID: 27211473.

Experimental food supplementation reveals habitat-dependent male reproductive investment in a migratory bird.

Kaiser SA, Sillett TS, Risk BB, Webster MS. Experimental food supplementation reveals habitat-dependent male reproductive investment in a migratory bird. Proc Biol Sci. 2015 Mar 22;282(1803):20142523. doi: 10.1098/rspb.2014.2523. PubMed PMID: 25673677; PubMed Central PMCID: PMC4345442.

An evaluation of independent component analyses with an application to resting-state fMRI

Risk BB, Matteson DS, Ruppert D, Eloyan A, Caffo BS. An evaluation of independent component analyses with an application to resting-state fMRI. Biometrics. 2014 Mar;70(1):224-36. doi: 10.1111/biom.12111. Epub 2013 Dec 18. PubMed PMID: 24350655; PubMed Central PMCID: PMC3954232.

Mixture of regressions with multivariate responses for discovering subtypes in Alzheimer’s biomarkers with detection limits. Data science in science

Mixture of regressions with multivariate responses for discovering subtypes in Alzheimer’s biomarkers with detection limits. Data science in science. . NIHMSID: NIHMS1978210.

A robust-design formulation of the incidence function model of metapopulation dynamics applied to two species of rails.

Risk BB, De Valpine P, Beissinger SR. A robust-design formulation of the incidence function model of metapopulation dynamics applied to two species of rails. Ecology. 2011 Feb;92(2):462-74. doi: 10.1890/09-2402.1. PubMed PMID: 21618925.